The effects of additive species, additive concentration, temperature, anode to cathode distance and current density on the electrochemical synthesis of tantalum ethoxide using sacrificing anode method have been investigated. The optimum conditions were tetramethylammonium chloride 0.04 mol/L, boiling temperature, distance 2 cm and current density 220 A/m2. After treating the mixed solution with general distillation and reduced distillation, the final product were characterized by fourier transform infrared(FTIR) spectrum, Raman spectra and elemental analyses. The product is tantalum penta-ethoxide. Current efficiency is more than 95%, and recovery ratio of tantalum during distillation is 82.8%.