The mechanical properties of Ti-6Al-4V alloy by laser rapid forming (LRF) have been investigated. The results show that the mechanical properties of the as-deposited Ti-6Al-4V alloy have the characteristics of higher strength, lower ductility and more distinct anisotropy properties as compared to wrought. The microstructure, content of oxygen and metallurgical flaw of the laser formed samples will have effect on the tensile test results. It is the microstructures that play crucial roles on the mechanical properties, while the oxygen content and ill-bonding flaw are in the next place. For the LRF Ti-6Al-4V alloy with the oxygen content meeting GJB GJB2921-1997, a basket weave microstructure obtained through the solution-aging treatment brings forth the best mechanical properties. Not only the strength but also the ductility is over than that of the wrought specification.