The microstructure and mechanical properties of ZK60 alloy sheet produced by different method were investigated using OM, SEM, TEM and a standard universal testing machine. The results show that, for conventional casting (CC) alloy, the equiaxed structure is refined after warm rolling. But for twin roll casting alloy, the microstructure changes from dendrite to fibrous deformed structure after warm rolling. Relatively higher density of shear bands can be observable in TRC ZK60 alloy sheet and no obvious dynamic recrystallization has been found after warm rolling. After warm rolling, the two alloys possess good mechanical properties, and the strength of TRC alloy is much higher than that of CC alloy, and elongation of TRC alloy is a little lower than that of CC alloy. The annealing heat treatment after warm rolling will induce a little decrease of strength and great increase of elongation of the two alloys. The tensile strength, yield strength and elongation of TRC and CC alloy sheet are 388 MPa, 301 MPa, 22.9%, and 311 MPa, 219 MPa, 19.3%, respectively. The grain refinement during manufacturing processes is attributed to the forma-tion of heavy shear bands, high density dislocation, twins, and the recrystallization during subsequent annealing proc-ess