In the present work, the hot compressive deformation test of TiNiCr alloy was carried out by using Gleeble-3500 in the strain rate range of 0.001 ~1s-1 and temperature range of 600~900℃. The microstructures of TiNiCr after deformation and the true stress-strain curves were studied. The results show that, the true stress-strain curves of TiNiCr alloy are affected by the work hardening and softening effect, the flow stress decreases with increasing temperature and decreasing strain rate. During hot compression, the dislocations which result in the hardening decrease because of the softening effect. Dynamic recrystallization occurs under all the deformation conditions and new grains are formed through grain boundaries bulging. The higher the temperature is and the lower strain rate is, the more obvious the dynamic recrystallization tendency is, the larger the grain size is and the more important role the dynamic recrystallization plays in the softening mechanism. TiNiCr alloy is different from the traditional non-intermetallic compounds, the softening mechanism can not be speculated only through the true stress-strain curves.