This paper reports the use of micro-arc oxidation(MAO) to prepare porous oxide coatings containing Ca and P on the surface of titanium and large plastic deformed titanium. The surface morphology, hardness, film-substrate bonding force, fretting friction and wear properties and bioactivity of MAO coatings on titanium and large plastic deformed titanium were investigated. Results reveal that compared with the MAO coating of conventional titanium, pores on the MAO coating of large plastic deformed titanium are more uniformly and compactly distributed, with smaller micro-sized pores, which have larger quantity, higher porosity, smoother and more level surface , larger relative content of rutile TiO2, higher hardness value, stronger adhesion strength. The improvements were caused by the increasement of crystal defects (internal energy) due to the microstructure refinement of large plastic deformed titanium.