The precursor powders were successfully prepared by GNP method with Ammonium molybdate((NH₄)₆Mo₇O₂₄.4H₂O), Cupric nitrate(Cu(NO₃)₂.3H₂O), Glycine and Ethylene diamine, followed by reducing in H₂ at 700℃ to convert into Mo-20Cu powders. Effects of different pressure on sintering body of Mo-Cu alloy that sintered at 1150℃ were studied. The results show that the nano-powders which is fine with size of 70~80nm can be prepared by GNP-H₂ reduction method. The relative density of Mo-Cu compact sintered at 1150℃ can achieve 99.7% of the theoretical and the microstructure of the compact distributes homogenously. With increase of pressure, the hardness, electrical conductivity and thermal conductivity will be enhanced with limit.