Ti6Al4V and 316L stainless steel impeller body were formed by electron beam selective melting (EBSM). By comparing the microstructure, dimensional accuracy, surface roughness, hardness, density and tensile strength of the impeller body, the feasibility of applying EBSM process in industrial impeller body manufacturing is evaluated. The results showed that: the tensile strength of Ti6Al4V and 316L stainless steel impeller body were 560MPa ~ 700 MPa and 996MPa ~ 1120MPa respectively, which were higher than the standard level of wrought, met the requirements of industrial use. The Ti6Al4V microstructure in the impeller body were basket-weave α+β, except those in leaf fragments were coarse flakes α + β phase because of their smaller cross-sections, and there were columnar crystals along the building direction. While the 316L stainless steel microstructure in the impeller body presented scaly scan path fusion marks, and there were some coarse dendrites.