NbCr₂/Nb-XMo (X=0, 2.5, 5.0, 7.5, 10at.%) alloys have been prepared by mechanical alloying and hot pressing. The effects of Mo on microstructures and properties of the NbCr₂/Nb alloy have been studied. The results show that the additions of Mo element do not change the phase components of the NbCr₂/Nb alloy, which are composed of Nb solid solution and NbCr₂. Adding alloying element Mo can increase the stress at the NbCr₂ / Nb phase interfaces, which promotes the increase of stacking fault /twinning in the NbCr₂ particles and the movement of dislocations in the Nb matrix. The NbCr₂ / Nb alloy adding with appropriate amount of alloying element Mo can maintain good plasticity and toughness as well as higher strength.