A new technology of the integral blisk was proposed recently to improve the thrust-to-weight ratio of the aero-engine, but which may result in high-risk failure near the disk-blade connection area. Therefore, here the molecular dynamics is used to simulate the mechanical properties of the single-crystal/polycrystalline nickel (SPSNi) in the joint zone. Firstly, the tensile atomic diagram of different crystalline nickels are compared. It is found that the degree of amorphization at the interface after tension is aggravated due to the presence of the single crystal/polycrystalline interface, which easily germinates void and exacerbates the risk of sudden fracture of SPSNi. Finally, the effects of the strain rate and temperature are especially investigated.When the strain rate is greater than 1í10_⁸s_^-1 and less than 2í10_¹⁰s_^-1, the tensile mechanical of SPSNi is almost insensitive to the loading strain rate, and the yield strength rises slightly.After exceeding 2í10_¹⁰s_^-1, the yield strength decreases rapidly with the increase of strain rate.This is because a large number of FCC atoms in SPSNi rapidly transform into disordered amorphous structure at high strain rate, resulting in the rapid decline of SPSNi carrying capacity. Strain rate 2í10_¹⁰s_^-1 can be used as the threshold of SPSNi tensile deformation. At different temperatures, the yield strength of SPSNi decreases linearly with increasing temperature, because the initial mosaic structure of dislocation network gradually becomes irregular, and the initial mismatch stress decreases with the increase of temperature under the influence of temperature.