Microstructure analysis, EDS analysis, mass loss experiment and electrochemical test were used to detect the corrosion performance of WE43 alloy after solution and solution-aging treatment. The result shows that heat treatment changes the second phase in the matrix to obtain different corrosion properties. The corrosion rate of solution-aging samples immersed for 0 and 6 h is higher than that of solution samples, and lower than that of solution sample immersed for 24 h. It is also found that during the corrosion process of WE43 alloy, the corrosion rate decreases first and then increases. Mathematical model was used to explain the relationship between the second phase and corrosion performance, and the reason why the corrosion rate changes with time.