Stem from high specific strength, low density, low elastic modulus, excellent mechanical properties, high temperature resistance and corrosion resistance, titanium alloy has become a promising candidate material to solve the high casing damage rate under heavy oil thermal recovery conditions. However, the study of titanium alloy slotted screens under thermal recovery conditions is still lacking. In this paper, the physical and chemical properties, axial thermal deformation, axial thermal stress, the change law of screen and slot shape of titanium alloy screen pipe under typical working conditions of heavy oil thermal recovery in Liaohe Oilfield were systematically investigated by finite element assistance (FEA) calculation and Full-size test, the results showed that titanium alloy screen had good strength and toughness properties under thermal recovery condition, the thermal stress of titanium alloy screen under 350 °C thermal recovery temperature was only 19.3 % and 20.4 % of that of CMS screen and composite screen. After seven cycles of thermal recovery temperature, the axial elongation of titanium alloy screen at 350 °C was only 58.7 % – 60.4 % of that of steel screen, under the large bending degree of 20° / 30 m and the high temperature of 350 °C, the titanium alloy screen had excellent deformation resistance, and the maximum ovality was only 4.13 %, the parallel slit remains intact and the sand control ability was better than that of the steel screen of the same specification. Based on this study, it can be considered that the titanium alloy screen and casing can effectively reduce the axial thermal stress and elongation of the thermal recovery pipe string in the thermal recovery condition, and had high temperature resistance and fatigue resistance, titanium alloy screen had good deformation resistance under the extreme bending condition of thermal recovery, which is one of the effective methods and development directions to solve the problem of high casing damage rate in heavy oil thermal recovery field in China, this study also provided technical reference for the design, use and management of titanium alloy screen.