In order to improve the wear and corrosion resistance of micro arc oxidation (MAO) coating on Ti-5Al-1V-1Sn-1Zr-0.8Mo alloy, 0-1.00g/l graphene oxide (GO) was added to the electrolyte to prepare micro arc oxidation coating. The thickness, roughness, micro morphology and composition of MAO coating were characterized, and the wear and corrosion resistance of the coating were tested and analyzed. The results show that with the increase of GO content, the thickness of coating increased from 102.3 μm to 115.3 μm. The roughness reduced from 56.7 μm to 32.9 μm. The diameter of micropore on the surface of the coating were about 10-60 μm without GO in electrolyte, and it decreased with GO. With 0.75 g/L and 1.00 g/L content, the diameter of micropore were stable at 10-20 μm. XRD results show that the content of rutile TiO₂ in the coating increases slightly with GO in eletrolyte, and the mass loss of the coating during wearing is significantly lower than that without GO. With 0.75 g/L GO, the binding force between coating and substrate alloy is the largest, reached to 53.3 N, which is 6.2 N higher than that without GO. After salt spray corrosion for 480 h, the coating with GO content of 0.75 g/L and 1.00 g/L have better corrosion resistance.