Indium tin (InSn) alloy nanowires were prepared using anodic aluminum oxide (AAO) film as template through vacuum mechanical injection method. Ru particles were then coated on the surface of InSn nanowires using the "in situ discharge reduction" method. Subsequently, the tin oxide nanowires (ITO NWs) was obtained by heat treatment of the composite material. Finally, RuO₂/ITO NWs were reduced in H₂ atmosphere to obtain Ru/ITO NWs. The results indicate that the diameter of InSn nanowire is about 40 nm and Ru nanoparticles of 2-5 nm are uniformly coated on the surface of ITO NWs. In addition, the catalytic pyrolysis of cellulose by Ru/ITO NWs was tested and the main products were 1,6-anhydropyranose, glycoladehyde, and hydroxyacetone. Compared the catalysate of ITO NWs without catalysts, Ru/ITO NWs catalyst reduces the production of 1,6-anhydropyranose, indicates that Ru nanoparticles exacerbate the fracture of oxygen bridges during pyrolysis, accelerate the generation of glycoladehyde and hydroxyacetone, and improve the pyrolysis efficiency. At the same time, the pyrolysis of nonylphenol polyoxyethylene ether with ether bonds is also carried out, and the result shows that Ru/ITO NWs plays a role in the fracture of ether bonds.