In this work, temperature range,microstructure evolution and corresponding mechnanical properties of sub-solvus and super-solvus were studied through experiment specimens; Thermal mechanical boundary conditions for simulation calculation were obtained through experiments; A method for designing heat treatment process of full-sized turbine disk components based on experiment and finite element analysis was proposed. The heat treatment process developed and implemented using this method has successfully prepared a full-sized dual-microstructure turbine disk, its microstructure and mechanical properties of different parts have been verified.