The W fiber reinforced Zr41.25Ti13.75Cu12.sNi10Be22.5 amorphous matrix composites with 50 mm in length and 6 mm in diameter have been produced by the melt infiltration casting method. The interface reaction appearance of the composite was analyzed by scanning electron microscopy at the same infiltration time and different infiltration temperatures. The interfacial shear strength of composite is determined by the push-out method. The relations between the macroscopically compressive fracture behaviors with the interracial characteristics and shear strength are discussed in the end. The results indicate that the plastic behaviors and fracture toughness of amorphous alloy were improved obviously, the interracial combination of composites included the two processes of interface diffusion and interface reaction, and the interracial shear strength increased when the interface reaction was pricked up. At the same time, the compressive failure mode of composite changed from the longitudinal split to the single shear failure.