Cu-13%Cr-0.24%Zr, Cu-15%Cr-0.24%Zr and Cu-15%Cr deformation in situ composite wires were prepared by cold drawing combined with intermediate heat treatments. The effects of Zr element, Cr content, intermediate annealing temperature and times on the ultimate tensile strength (UTS) and electrical conductivity of Cu-Cr composites were investigated. Results show that Zr element can significantly enhance the UTS, while its effect on the electrical conductivity is modest. With the increase of mass friction of the Cr element, the UTS tends to increase a bit, and it has little impact on the electrical conductivity. Increasing annealing temperature or times can decrease the UTS and improve the electrical conductivity. In the experiment Cu-15%Cr-0.24%Zr in situ deformation wires with excellent comprehensive properties were obtained through the process of twice intermediate annealing at 500 °C, whose UTS reaches 1056 MPa and whose electrical conductivity reaches 73%IACS