Sliding wear tests were performed of TC4 alloy/GCr15 steel on the MPX-2000 pin-on-disk wear tester. The effect of nano-oxide particles artificially supplied onto the sliding interface on the wear behavior of TC4 alloy was studied by varying the type and diameter of oxide particles. The wear characteristics of alloy were examined by XRD, SEM and EDS, the wear mechanism of TC4 alloy being discussed subsequently. Results showed that the type and diameter of oxide particles had significant influences on the wear behavior of TC4 alloy. Its wear loss was aggravated fleetly by TiO₂ oxide particles, whereas it was improved in the case of Fe₂O_3. The wear loss of TC4 alloy was getting smaller with the decreasing particle diameter of Fe₂O₃, which was almost independent of the applied load. When the TiO₂ was supplied, the wear mechanism of TC4 alloy was mainly abrasive and adhesive wear as the same as that without any additives. The severe-to-mild wear transition occurred when Fe₂O₃ oxide particles were supplied.