Using the technology of split Hopkinson bar, dynamic mechanical experiments under high strain-rate loading on hat-shape samples of TC6 titanium alloy with binary structure have been conducted and the fracture failure mechanism has been investigated. It is shown that the fracture of TC6 titanium alloy with binary structure is often related to adiabatic shear band when deformed at the high strain rate. Its fracture includes three stages, i.e. nucleation of voids, growth of voids to form micro-crack and expansion of the micro-crack to form fracture