In this research, the effect of phytic acid on bioactivity of the surface of SLA-titanium was studied, through modification with phytic acid and subsequent mineralization in the simulated body fluid (SBF). The microstructure, chemical properties and wettability was demonstrated, using SEM、EDS and contact angle analysis. Human bone marrow stromal cells (hBMSCs) were cultured on different surfaces to investigate the proliferation, adhesion and differentiation. The results demonstrate that the contact angle of surface modified with phytic acid is 0°, which means it is superhydrophilicity. The ability to induce apatite deposition, as well as the proliferation, adhesion differentiation of cells are improved obviously on SLA-surface, which reflect a better bioactivation treatment as a result of using phytic acid solution.