Sn is a kind of low melting point metal and can be used as a liquid coolant due to its higher thermal conductivity. Compared with the currently used sodium liquid coolant, Sn is more chemical stable and unfeasible to fire or explore when contacting with air or water. In this paper we examined the chemical reactions between Sn and 304 stainless steel, which is widely used as primary circuit pipeline materials in fast reactor, and discussed the effect of temperature on the corrosion behavior between 304 stainless steel and liquid Sn. The results showed that pitting happened when the temperature was lower than 823K, and dissolution happened when the temperature was higher than 823K.