彭书浩,李慕勤,王晶彦,田钦文.纯钛表面载骨碎补提取物涂层的制备与性能[J].稀有金属材料与工程,2019,48(6):1921~1928.[Peng Shuhao,Li Muqin,Wang Jingyan,Tian Qinwen.The preparation and property of coatings of carrying extract of Rhizoma Drynariae on the surface of pure titanium[J].Rare Metal Materials and Engineering,2019,48(6):1921~1928.]
纯钛表面载骨碎补提取物涂层的制备与性能
投稿时间:2018-01-22  修订日期:2018-03-26
中文关键词:  纯钛  微弧氧化  骨碎补提取物  耐蚀性  生物活性
基金项目:国家自然科学基金资助(项目号31370979)
中文摘要:
      为了提高纯Ti的生物活性和抗感染性,采用微弧氧化(UMAO)制备多孔涂层,并以植酸(PA)偶联骨碎补提取物(ERD),并分析涂层结构、形貌及性能。结果表明,随着ERD浓度的提高,纳米颗粒增多,有PO43-,P2O74-和O=P-O-生成;载药12.5g/L的膜层摩擦磨损系数低,膜层结合力较高,为亲水涂层,膜层的电位提高了0.32V,自腐蚀电流降低一个数量级,模拟体液浸泡有羟基磷灰石(HA)生成。纯钛表面通过超声微弧氧化,植酸偶联载药的耐蚀性,结合力,生物活性均有提高。
The preparation and property of coatings of carrying extract of Rhizoma Drynariae on the surface of pure titanium
英文关键词:micro  arc oxidation, Rhizoma  Drynariae, phytic  acid, bone  repairing material
英文摘要:
      To improve the bioactivity of surface of titanium and reduce infection rate of implantation, the porous coatings were prepared by ultrasonic micro arc oxidation (UMAO) and Rhizoma drynariae(ERD) coupled by phytic acid .Besides, the structure, surface morphology and performance were investigated. The results indicated that nanoSparticles of drug loading increased with concentration of ERD. The surface of coatings produced PO43-,P2O74- and O=P-O-. The friction coefficient of 12.5 g/L was lower .Also, the coating of 12.5 g/L had a better binding force and was hydrophilic. The potential increased by 0.33-0.45V and self-corrosion current decreased by a order of magnitude for concentration of 12.5 g/L. In conclusion, the corrosion resistance, binding force and bioactivity are improved by drug loading coupled with phytic acid after MAO on the magnesium.
作者单位E-mail
彭书浩 佳木斯大学 黑龙江省高校生物医学材料重点实验室 502463561@qq.com 
李慕勤 佳木斯大学 黑龙江省高校生物医学材料重点实验室  
王晶彦 佳木斯大学 黑龙江省高校生物医学材料重点实验室  
田钦文 佳木斯大学 黑龙江省高校生物医学材料重点实验室  
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