In order to investigate the hot deformation behavior of TC17 titanium alloy, isothermal compression tests on a Gleeble 3500D simulator were carried out in a temperature range of 973-1223 K, the strain rate range of 0.001-10s_-1 and strain of 0.9. The results indicated that the flow stress was sensitive with deformation temperature and strain rate. Meanwhile, discontinuous yielding phenomenon was found at the strain rate of 10s_-1 with temperature of 1123K, 1183K and 1223K. Based on multiple regression, a constitutive model was put forward to describe the role of the flow stress as the Zener-Holloman parameter. Thereafter, the processing map on the basis of dynamic materials model was established, and the validity of the developed processing map was verified by using the microstructure of compressed TC17 titanium alloy.