The effects of percentage reduction per pass (PRPP) on the effective strain, microstructure, mechanical properties and through-thickness homogeneity of AA7055 alloy plates were investigated through experiments and numerical simulations. Results show that with consistent total strain, the difference between the effective strain values in the surface and middle layer of AA7055 alloy plates decreases with the increase of PRPP. In the plate rolled with small PRPP, the surface layer of plate contains higher recrystallization fraction, while the middle layer comprises of large recrystallized grains. In contrast, the plate rolled with large PRPP has consistent recrystallized grain size with consistent recrystallization fraction along the thickness direction. Thus, an improved homogeneity of the microstructure and mechanical properties along the plate thickness direction can be obtained through the rolling process with large PRPP.