A new process of laser-induction hybrid quenching was adopted in this paper, which combined the laser and electromagnetic induction heat source to improve the depth and uniformity of hardened layer. The COMSOL Multiphysics 5.5 software was used to analyze the evolution process of temperature field in hybrid quenching process of 42CrMo steel. The model was verified by experiments and the simulated depth of hardened layer was in good agreement with the experimental one. The surface temperature and depth of hardened layer by the hybrid quenching, single laser quenching and single induction quenching were compared in the model, and the effects of different scanning speed and laser spot size on the depth of hardened layer were analyzed. The results show that the hybrid quenching can effectively improve the surface quenching temperature of the workpiece, increase the width and depth of the hardened layer, and make up for the shortage of the single laser quenching power. The optimal scanning speed and laser spot size of the hybrid quenching were predicted by the model. Compared with two single quenching，the change trend of grain size and microstructure in depth direction of the hybrid quenching is similar to that of the laser quenching and the average hardness of hardened layer is larger.