Uranium metal and its alloys played important roles in the files of nuclear industry, working as configurational or functional materials. The corrosion behavior of them attracted people"s interest because it would greatly affect the materials" performance. Material factors, including components, microstructures, defects in body and on the surface, were the internal causes to affect the corrosion resistance of uranium materials. This paper conducted a review on how the defects of uranium materials affected their corrosion behavior. We summarized the reported works from four aspects: impurity, inclusions, microstructures and surface states. Strategies to improve the corrosion resistance of uranium materials by means of modulating these defects were also briefly discussed.