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牙科植入物Zr-30Ti-xCu合金显微组织及性能研究
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上海大学 材料研究所

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TG146.4+14;TG156.31

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Microstructure and Properties of Dental Implant Zr-30Ti-xCu Alloys
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Institute of Materials, Shanghai University

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    摘要:

    锆(Zr)及其合金具有较低的弹性模量、良好的耐腐蚀性能和优异的生物相容性,近年来在牙科植入物候选材料中得到了广泛关注。本工作以Zr为基体,结合价电子浓度理论设计了成分为Zr-30Ti-xCu(x = 0、3、7,质量分数,%)的新型合金。使用SEM/EDS和TEM/EDS等表征了该合金的显微组织,通过显微硬度测试、室温拉伸实验、电化学测试、接触角测试和抗菌性能实验表征了该合金的力学性能、腐蚀行为、生物相容性与抗菌性能。结果表明:通过650 ℃/15 min淬火工艺处理后3种合金基体主要为β相,添加Cu后合金基体中析出了Zr2Cu第二相,且随着Cu含量的增加,Zr2Cu第二相数量增多。随着Cu含量的增加,维氏显微硬度提高了37%,接触角从98.49°减小至74.21°,表面润湿性提高,对于大肠埃希氏菌和金黄色葡萄球菌表现出明显的抑制作用,且增强了合金在生理盐水中的耐腐蚀性能;3种合金均具有较低的弹性模量(67.8~78.9 GPa)和细胞毒性,但与Cu含量的关系不大。可见,Zr-30Ti-xCu合金表现出了较优异的综合性能,可为新型牙科金属植入物的选材提供理论依据和指导。

    Abstract:

    Zirconium and its alloys have recently received considerable attention as candidate materials for dental implants due to its low modulus of elasticity, good corrosion resistance, and excellent biocompatibility. In this work, Zr-30Ti-xCu (x=0, 3, 7, mass fraction, %) alloys were designed by the valence electron concentration (VEC) theory. The microstructures of the alloys were characterized using SEM/EDS and TEM/EDS. The mechanical properties, corrosion behaviors, biocompatibility and antibacterial activities of the alloys were characterized through microhardness testing, room temperature tensile testing, electrochemical testing, contact angle testing, and antibacterial performance experiments. Results showed that after quenching at 650 ℃/15 min, the three alloy matrices were mainly composed of β phase. In the Cu-containing alloys, Zr2Cu second phase precipitated and the number of Zr2Cu particles increased with the increase of Cu content. With the increase of Cu content, the Vickers microhardness increased by 37 %, the contact angle decreased from 98.49° to 74.21° to improve the surface wettability. Meanwhile, it showed a significant inhibitory effect on Escherichia coli and Staphylococcus aureus, and enhanced the corrosion resistance of the alloy in physiological saline solution. The three alloys had low elastic modulus (67.8-78.9 GPa) and cytotoxicity, but their relationship with Cu content was not obvious. It can be seen that Zr-30Ti-xCu alloy exhibits excellent comprehensive properties, which can provide theoretical basis and guidance for the selection of new dental metal implants.

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陈哲斌,崔越,胡丽娟,马润泽,徐诗彤,姚美意.牙科植入物Zr-30Ti-xCu合金显微组织及性能研究[J].稀有金属材料与工程,,().[Chen Zhebin, Cui Yue, Hu Lijuan, Ma Runze, Xu Shitong, Yao Meiyi. Microstructure and Properties of Dental Implant Zr-30Ti-xCu Alloys[J]. Rare Metal Materials and Engineering,,().]
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  • 收稿日期:2024-10-09
  • 最后修改日期:2024-12-04
  • 录用日期:2025-01-03
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