Abstract:Zirconium and its alloys have recently received considerable attention as candidate materials for dental implants due to its low modulus of elasticity, good corrosion resistance, and excellent biocompatibility. In this work, Zr-30Ti-xCu (x=0, 3, 7, mass fraction, %) alloys were designed by the valence electron concentration (VEC) theory. The microstructures of the alloys were characterized using SEM/EDS and TEM/EDS. The mechanical properties, corrosion behaviors, biocompatibility and antibacterial activities of the alloys were characterized through microhardness testing, room temperature tensile testing, electrochemical testing, contact angle testing, and antibacterial performance experiments. Results showed that after quenching at 650 ℃/15 min, the three alloy matrices were mainly composed of β phase. In the Cu-containing alloys, Zr2Cu second phase precipitated and the number of Zr2Cu particles increased with the increase of Cu content. With the increase of Cu content, the Vickers microhardness increased by 37 %, the contact angle decreased from 98.49° to 74.21° to improve the surface wettability. Meanwhile, it showed a significant inhibitory effect on Escherichia coli and Staphylococcus aureus, and enhanced the corrosion resistance of the alloy in physiological saline solution. The three alloys had low elastic modulus (67.8-78.9 GPa) and cytotoxicity, but their relationship with Cu content was not obvious. It can be seen that Zr-30Ti-xCu alloy exhibits excellent comprehensive properties, which can provide theoretical basis and guidance for the selection of new dental metal implants.