As a kind of material which is particularly sensitive to the parameters of hot working process, the flow stress of the In706 superalloy was investigated using the isothermal compression tests at 1143K-1393K and strain rate of 0.01, 0.1, 0.5 and 1 s^-1, and the reduction of 30%, 45%, 60%. The exponent-type Zener-Hollomon equation was used for the impact of strain and temperature on thermal deformation. Meanwhile, the strain effect of various material constants such as α, n, Q, and lnA was included in the constitutive equation considering strain compensation, and the correlation coefficient R and the average absolute relative error AARE were verified in this prediction. On the basis of constitutive equation construction, the hot processing map of In706 superalloy was drawn, and the instability region was given based on Murty criterion, and the reasonable thermal working process parameter window was selected as strain rate 0.1s^-1 condition, temperature range 1313~1353K.