A K2Ti6O13 bio ceramic coating on the surface of titanium alloy TiAlxZrx- 4Snx- 3.5Nbx- 4.5 was prepared by using an in situ kneading drying calcination synthesis technique. During emersion in a simulated body liquid the microstructure, composition of phases, bonding strength between the coating and matrix, and the bio activity of the coating were evaluated. The test results indicated that the bond strength between the coating and the matrix was high enough to resist cool and hot impact during air cooling mainly as a result of the good thermal expansion match between the coating and the matrix. Rough surfaces and small holes on the Ti alloy coating provided sites for simulated bone attachment. Soaking of the coated alloy in a simulated body liquid, encouraged the active formation of a Ca P layer with a ratio of Ca and P appropriate to human bone .