Acid-proof Ti based-MO2 anodes with SnO2+Sb2O4 intermediate layer were prepared by thermal decomposition method, the surface characterization of the electrodes were studied by scanning electron microscopy (SEM), elements composition and valence state of SnO2+Sb2O4 intermediate layers were analyzed with X-ray Diffraction (XRD) and X-ray Photoelectron Spectroscopy (XPS), respectively. The polarization curves of oxygen evolution and high density (4 A/cm2) lifetime of Ti/SnO2+ Sb2O4/MnO2 and Ti/ SnO2+Sb2O4/PbO2 anodes were determined in 1.0 mol/L H2SO4 solution. Their potentials of initial oxygen evolution were lower than those of moble metals, and their lifetimes reached 18 h and 86 h, respectively. The experiment showed that the combination of SnO2+Sb2O4 is a better intermediate layer material and will play a important role in Ti/MnO2 and Ti/PbO2 anodes.