CuCo catalysts used for synthesis of low-carbon alcohol by CO+H2 were prepared by the reverse coprecipitation method under the ultrasound irradiation. The influence of rare earth Ce assistant on the structure and catalytic properties was investigated. The experimental catalysts were extensively characterized by XRD, BET, TPR and TPD techniques. It was found that after the addition of rare earth Ce, the crystallite size of the catalytic material was decreased, the reducibility was enhanced, the specific surface area was increased and the formation of the active sites for alcohols was improved significantly. Therefore, the activity and selectivity of the rare earth promoted catalyst were improved remarkably.