High temperature compression simulation tests were carried out on Ti8LC alloy at a constant strain rate by a GLEEBLE-1500 thermal simulator, under the conditions of 850-1000 oC, 0.001-0.1 s-1 and maximal deformation of 60%. The effects of the strain rate and the forming temperature on the flow stress and the microstructure transition were investigated. The results reveal that the flow stress of Ti8LC increased as the strain rate increased, and at a constant strain rate the true stress decreased as the forming temperature increased. In the situation of experiment, the constitution equation of Ti8LC alloy was established by regression calculation. According to the experimental analysis, dynamic recrystallization happened while deformed at 850-950 oC. In addition the dynamic recovery was the mainly softening mechanism at evaluated temperature.