The pure vanadium was prepared by hot isostatic pressing (HIPing). The mechanical properties of the pure vanadium were examined and the tensile fracture, microstructure and thermal change of the specimen were analyzed by a material testing machine, OM, SEM, TEM and TGA. The results show that pure vanadium can be up to full densification at the HIPing temperature above 1250 oC. With increasing of the temperature, the tensile strength and yield strength decreases at first and then increases, but the plasticity change is on the contrary. Its comprehensive mechanical properties are best at 1250 oC, e.g. the tensile and yield strength are 701 MPa and 634 MPa, respectively, and the elongation is up to 22.4%. Fracture of the specimens happens in the modes of slipping off or micro-porous aggregation. The grain sizes of pure vanadium prepared at different temperatures are similar, and lath-like martensite is observed in all of the specimens. The oxidation processes follow parabolic kinetics, whose activation energy is 118 kJ/mol.