Mo-Ti-TiC alloys were fabricated by powder metallurgy process through adding TiH2 powder and ultrafine TiC powder into Mo metal. The influence of the addition of nano-scale TiC particles on the microstructure and tensile properties of Mo-Ti alloy was studied. The results indicate that the tensile strength of Mo-Ti alloy was effectively increased by TiC particles addition. Mo-Ti with 0.05wt% TiC exhibited the highest tensile strength, which is 31.7% higher than that of Mo-Ti alloy. The addition of TiC protects Ti from oxidation, which is produced by decomposition and dehydrogenization of TiH2 particles. The second phase particles containing Mo, Ti, O and C in the alloy were formed with TiC addition. The grain size of the alloy decreased with the increase of the TiC content since the second phase particles can inhibit the grain growth