Effects of the surface morphology of micropatterned NiTi alloy, an intravascular stent material, on the adhesion of bovine aortic endothelial cells (BAECs) and blood platelets were investigated. Mechanical polishing, chemical pickling and sandpaper grinding were used to prepare NiTi alloy with micropores and microgrooves. The surface morphologies and average roughness (Ra) were characterized by SEM and surface profilometer. The effects of the material surface with micropores and microgrooves on the adhesion of blood platelets and endothelial cells were determined. Results show the NiTi alloy surface with micropores or microgrooves could be controlled in the range of nanometer. Both of these two micriopatterned surface could enhance BAECs adhesion, but the effect on platelet adhesion is not obvious; the number of BAECs adhesion on surface with micropores were significantly more than that on the surface with microgrooves. Furthermore, the cells in the surface with micropores show a good growth situation. The microgroove structure has contact-induction effect on the early adhesion of the cells