The hot deformation behavior of the cast Ni-35Cr based GH4648 superalloy was studied though hot compressing testing on a Gleeble-1500 simulator. The results show that the onset temperature of the dynamic recrystallization (DRX) in the cast GH4648 alloy is 1050 oC. The DRX process is going more sufficient with higher temperature. Below 1050 oC, there is no DRX grain. The effect of homogenization heat treatment on the hot working ability of cast GH4648 alloy was studied. After homogeneous heat treatment at 1180 oC for 45 h, the DRX process is restrained and resistance of deformation is increased.