The oxidation behavior of Ti600 alloy at high temperature was investigated. Thermodynamic and dynamic laws were studied by means of calculating the oxidation mass gain, oxidation rate constants and activities. The phase structure and morphology of oxidation scales on surface were examined with XRD and SEM. The element distribution profile along cross-section of the oxidation layer was studied by EDS to understand the diffusion behavior. The results indicate that Ti600 alloy exhibits the parabolic rule of oxidation rate at 600~700 ℃, but obeys the parabolic-linear rule at 750 ℃. The oxidation scales are composed of TiO2 and Al2O3.