The microstructure evolution during isothermal compression at different deformation temperatures and strain rates and water quench after β heating of near-α TA15 titanium alloy with initial equiaxed microstructure was investigated using X-ray diffraction (XRD)，electron backscatter diffraction (EBSD) and transmission electron microscopy (TEM) analysis．The tensile strength and elongation were measured by conducting micro-tensile property tests．The results show that α phase globularization occurs when the alloy is deformed at α β temperature range．High temperature β phase transforms into martensite α'' after water cooling．The alloy is composed of equiaxed α，lamellar secondary α and acicular martensite α''．When the alloy is compressed at β temperature range，the microstructure is basically acicular martensite α'' phase．At the temperature range below or above phase transformation point，with the increasing of temperature，the tensile strength decreases and the elongation increases．But at the temperature ranges around phase transformation point，with the increasing of temperature，the tensile strength increases and the elongation decreases．At the two-phase region near phase transition point，better strength and plasticity can be obtained．