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Blood Compatibility of TiO2-HA Bioceramic Coating on Titanium
Affiliation:

School of Mechanical Engineering,Jiangsu University,,School of Mechanical Engineering,Jiangsu University,Laboratory Animal Research CenterS,Jiangsu University,Laboratory Animal Research CenterS,Jiangsu University

Clc Number:

R138

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    Abstract:

    Modified titanium materials, including TiO2 and TiO2-HA bioceramic coatings, were prepared by micro-arc oxidation and micro-arc oxidation-hydro-thermal methods. Determination of the hemocompatibility of the coatings through a hemolysis experiment, dynamic clotting time test, and platelet adhesion experiment was also performed. The results demonstrated that: Hemolysis rates of all samples were less than 5%, no hemolysis was observed. Compared with titanium and TiO2 bioceramic coating of titanium, TiO2-HA bioceramic coating of titanium exhibited lower hemolysis rate, slower change in dynamic clotting time and less platelet adherence. The proposed TiO2-HA bioceramic coating further showed a lower degree of deformation, better inhibition of platelet aggregation and deformation, and excellent hemocompatibility.

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[Xu Lin, Ding Jianning, Xu Xiaojing, HeYuanqing, Lei Xiaochun. Blood Compatibility of TiO2-HA Bioceramic Coating on Titanium[J]. Rare Metal Materials and Engineering,2017,46(5):1299~1304.]
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History
  • Received:January 15,2015
  • Revised:March 06,2015
  • Adopted:May 13,2015
  • Online: September 27,2017