ITO nanopowders were prepared by chemical coprecipitation , NH₄Cl-NH₃H₂O,(NH₄)₂SO₄-NH₃H₂O and NH₄AC solution were used as buffer solution to remain the pH value unchanged, simultaneously, the powders were prepared with different dispersants, the effects of buffer solution and dispersant on pHase structure,morpHology ,conductivity and the dispersion were characterized by XRD, TEM,FourSpoint probe and BET .The results show that the powders prepared with the buffer solution is single-pHase In₂O₃ structure.When the nanopowders prepared under the conditions of NH₄AC as buffer solution, soluble starches as dispersant, the pH value 6 to 7, the obtained powder is with about 10 nm particle size,uniform particle size, and good dispersibility ,and simultaneously the powders is inerratic cubic shape with relatively good electrical conductivity.