The ω phase transformation of Ti-1300 alloy under 20MPa compressive stress during continuous heating was investigated using high resolution dilatometer DIL 805 A/D. Results show that the ω phase transformation of Ti-1300 alloy could be inhibited by 20MPa compressive stress during continuous heating. The local activation energy of ω phase transformation for Ti-1300 alloy was determined on the basis of Kissinger–Akahira–Sunose(KAS) method. The average activation energy of ω phase transformation is about 73 KJ/mol under 20MPa compressive stress, which is higher comparing with no stress condition (55KJ/mol ). However, the compress stress was able to certain inhibit the ω phase transformation of Ti-1300 alloy during continuous heating. Therefore, owing to the activation energy decresed with increase of transformed volume fraction fω, the inhibiting effect of compressive stress on ω phase transformation of Ti-1300 alloy was gradually weakened.