Ni-Al (molar ratio is 1:1) energetic structural material (ESM) was prepared by cold-pressing and sintering with Ni and Al elemental powders. The effect of sintering temperature on the interface diffusion, mechanical properties ,initial reaction temperature and energy density of Ni-Al energetic structural materials was investigated. The results demonstrate that the increasing sintering temperatures result in increase in the rate of diffusion, boundary adhesion strengthSand mechanical properties of Ni-Al ESM while the decrease in energy density. The ESM with excellent combination of both energy density and mechanical properties can be obtained by sintering Ni-Al green body at 550 ℃, of which the tensile and compressive strengths are 66.0 MPa and 294.6 MPa, respectively, the energy density is 436.1 J/g .