Short time stress rupture properties (10 min~3 h) of GH4098 alloy have been investigated at different temperatures (800~1000 °C) and stresses (90~680 MPa) after solution and aging treatment, combined with the characterization of microstructures and fracture features. The results show that fracture features of GH4098 alloy are ductile and intergranular in all temperature range. Short time stress rupture properties of the alloy degrade gradually with increasing the testing temperature, but they are significantly worse at 1000 °C. Microstructural characterization indicates that there is little change in grain size with increasing the temperature. The deterioration of short time stress rupture properties at higher temperature is ascribed to the reduction of γ’ volume fraction as well as the coarsening of γ’ precipitates and grain boundary carbides. In addition, the influence of cooling rate on microstructures as well as the differences between short time creep and traditional creep was also discussed