This study developed a new preparation process for titanium powder for additive manufacturing- Wire Induction heating Gas Atomization (WIGA). The combination of numerical simulations and experimental investigations was used to investigate the high frequency induction melting of titanium wire. The numerical simulations obtained the optimal parameters of the titanium wire induction melting model. The angle α of the induction coil is 90°. The power output frequency f is 450 kHz. The diameter of the titanium wire was 4mm, and the minimum wire feed speed was 45 mm/s when forming a 15 mm length of metal flow. Under this condition, the critical output power is 34kW when the molten metal generates 350±50°C of superheat. An argon atmosphere protective titanium melting experimental device was established. Through experimental investigations, the minimum TC4 wire feed speed was 50 mm/s when forming a 15 mm length of metal flow，and the error between the experimental and the numerical simulation was 10.0%. Under this condition, the minimum output power of the power supply was 38kW when generating a molten metal with a superheat of 350±50°C, the experimental and numerical simulation errors were 10.5%. The experimental and numerical simulation results proved each other, and the engineering application basis of high frequency induction melting of titanium wire was obtained.