A series of plate-type V₂O₅-MoO₃-Nd₂O₃/TiO₂ catalysts with different amounts of neodymium were prepared to investigate the impact of neodymium addition on selective catalytic reduction (SCR) of NO with NH₃. XRD, N₂-adsorption, XPS, H₂-TPR, Raman and NH₃-TPD were carried out to characterize the catalysts. It was found that with the suitable addition of Nd (0.25% and 0.5%) to V₂O₅-MoO₃/TiO₂ catalyst not only brought to the improvement of the reduction property, but also increased the O_α/(O_α+O_β) ratio of the catalyst, which leaded to the enhanced catalytic efficiency. However, when the content of Nd was excessive (0.75% and 1%), the acid sites of the catalysts decreased evidently. Accordingly, the catalytic performance of these catalysts was relatively low. What is more, the mechanical property of the catalyst declined when the content of Nd was excessive. Among the catalysts investigated, VMoNd(0.5%)/Ti catalyst had the best catalytic performance.