The intermediate dense and surface porous Ti-13Nb-13Zr gradient alloy was fabricated by spark plasma sintering(SPS). The effect of sintering temperature (950~1200℃) on the microstructural evolution, interface bonding, surface porosity, mechanical properties and in vitro mineralization properties of gradient alloy were investigated. The results show that the a-Ti phase in the gradient alloy decreases,and the β-Ti phase increases with the gradual increase of the sintering temperature, then the structure is gradually continuous and uniformly distributed, the grains are refined, and the interface between the intermediate matrix and the porous layer is continuously transitioned well formed with metallurgical bonding.The porosity of the surface porous layer decreases and the average pore diameter decreases.The compressive strength value of the gradient alloy firstly increases and then decreases with the increase of the sintering temperature, while the compressive elastic modulus value slightly changes.Based on the above analysis, it shows that at the 1150℃ sintering temperature, the fabricated surface porous gradient alloy not only has good mechanical properties (compressive strength 893MPa, compressive elastic modulus 16GPa), but also has suitable pore parameters (porosity 34.7%, average pore diameter 340.9um) and excellent bone-like apatite forming ability together with in vitro mineralization performance.