In this paper, a new high-strength corrosion-resistant titanium alloy is taken as the research object. The effect of annealing process on the microstructure and properties of the plate were studied. After annealing, the overall structure is uniformly distributed. As the annealing temperature increases, the lamellar α phase decreases, the equiaxed α phase increases, and the β-transformed structure grows and increases. When annealed at 740℃, the lamellar α phase basically disappears, the β-transformed structure grew, increased and struck together, showing a typical equiaxed structure. As the annealing temperature increases, the strength and hardness of the plate decrease, the plasticity increases, the corrosion current density decreases, the corrosion rate decreases, and the corrosion resistance increases. After annealing at 740℃ for 1 hour, the plate has the best mechanical properties and corrosion resistance.