3D through-hole Pb-Ca-Sn anode was prepared which may be a promising anode with excellent performance for copper electrowinning. And the electrochemical properties of 3D through-hole Pb-Ca-Sn anode and Pb-Ca-Sn anode were studied by galvanostatic polarization, electrochemical impedance spectroscopy, anodic polarization and double-Slope Tafel carried out in 160 g/L H₂SO₄ solution at 45 °C. Besides, the micro-morphology, element distribution and phase composition of the oxide layer were investigated. Results show that compared with the traditional Pb-Ca-Sn, 3D through-hole Pb-Ca-Sn anode shows much lower anodic potential, higher exchange current density and better electrocatalytic activity. These characteristics are related to its excellent 3D through-hole structure, which increases the oxygen evolution surface area of the anode. Furthermore, the content of β-PbO₂ and PbSO₄ in the oxide layer of 3D through-hole Pb-Ca-Sn is higher and lower than those of Pb-Ca-Sn, respectively.