Magnesium-strontium series alloys are one of the most prospective biodegradable metal materials, which perform well in biocompatibility because strontium has the function of promoting osteogenesis and regeneration. But the shortcomings of magnesium alloys such as inadequate strength and rapid degradation rate still exist. In the present study, an appropriate amount of human nutrient element zinc was added into Mg-2Sr alloy. Since the solid solution effect of zinc in the alloy can refine the grains, the strength and plasticity of Mg-2Sr alloy are improved. Results show that the Mg-2Sr-2Zn alloy has better corrosion resistance during the degradation processing. The corrosion protection layer is relatively dense, which hinders the penetration of chlorine ions in the simulated body fluid during the soaking process.