: TiZrHf medium entropy alloy and pure Ti were prepared in vacuum arc furnace. The equiaxed grains were obtained by cold rolling and annealing, and their phase composition was studied by X-ray diffraction. Scanning electron microscope and Electron back scattered diffraction was performed to study the microstructure and in-grain slip activities of TiZrHf alloy and pure Ti. The results show that both TiZrHf alloy and pure Ti are single-phase HCP structure with approximately the same axial ratio, and their texture are basal texture after recrystallization. The pyramidal slip of TiZrHf alloy occupy a high fraction of～26% at 10% tensile strain along RD, which is twice the proportion of pyramidal slip in pure Ti, and the number of {10-12} tensile twins is significantly more than that of pure Ti.