The effect of surface etching by H₂C₂O₄ and H₂SO₄ on Ti substrates on the electrochemical properties and surface morphologies of titanium oxide anode was investigated through different etching methods. The scanning electron microscope, X-ray diffraction, and X-ray photoelectron spectroscopy were used to analyze the specimen structure. The electrocatalytic activity and the electrochemical stability of the specimens were also evaluated by the electrochemical workstation and accelerated lifetime tests, respectively. Results show that the dual acid etching can achieve denser and more homogeneous surface with better catalytic stability. In addition, the influence mechanism of pretreatment on the lifetime of Ti anodes was discussed. The catalytic activity and stability of IrO₂-Ta₂O₅/Ti anodes are strongly dependent on the sequence of acid etching and the surface structure of anodes, and thereby the relationship between the pretreatment methods and the anode performance is established. The dual acid etching can achieve a Ti surface with moderate roughness, therefore improving the coating adhesion. The titanium hydride formed through the dual acid-treatment is transformed into the rutile with barely changed surface morphology, which is conducive to the electrons transport. Therefore, the coating adhesion is enhanced and the accelerated lifetime is prolonged.